Biocuration with insufficient resources and fixed timelines

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Biocuration with insufficient resources and fixed timelines

Biological curation, or biocuration, is often studied from the perspective of creating and maintaining databases that have the goal of mapping and tracking certain areas of biology. However, much biocuration is, in fact, dedicated to finite and time-limited projects in which insufficient resources demand trade-offs. This typically more ephemeral type of curation is nonetheless of importance in ...

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Shared resources, shared costs—leveraging biocuration resources

The manual curation of the information in biomedical resources is an expensive task. This article argues the value of this approach in comparison with other apparently less costly options, such as automated annotation or text-mining, then discusses ways in which databases can make cost savings by sharing infrastructure and tool development. Sharing curation effort is a model already being adopt...

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Exploration and Exploitation with Insufficient Resources

In physical experimentation, the resources available to discover new knowledge are typically extremely small in comparison to the size and dimensionality of the parameter spaces that can be searched. Additionally, due to the nature of physical experimentation, experimental errors will occur, particularly in biochemical experimentation where the reactants may undetectably denature, or reactant c...

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Model-Checking with Insufficient Memory Resources

Resource limitations is a major problem in model checking. Space and time requirements of model-checking algorithms grow exponentially with respect to the number of variables and parallel automata of the analyzed model. We present a method that is the result of experiences from a case study. It has enabled us to analyze models with much bigger state-spaces than what was possible without our met...

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ژورنال

عنوان ژورنال: Database

سال: 2015

ISSN: 1758-0463

DOI: 10.1093/database/bav116